Indications

• Hypertension
• CKD with Hypertensive patients
• Renal parenchymal hypertension
• Diabetic nephropathy
• Long-term prophylactic management of angina pectoris

Dosage

• Hypertension: 2-4 mg once daily up to 8 mg once daily needed
• Angina pectoris: 4 mg twice daily

How it should be taken

• It is available in tablet form and should be administered through mouth with food

Contraindications

• Pregnancy and lactation

Common side effects

• Palpitation, facial flushing, hot flushes, headache, dizziness, sleepiness, constipation, nausea, abdominal discomfort, oedema, malaise, redness and warm feeling in the fingers, shoulder stiffness, increased frequency of micturition.
• Hypersensitive reactions e.g. rash and itching
• Elevation of SGOT, SGPT, alkaline phosphatase, total bilirubin, creatinine and uric acid.

Precautions to be taken

• It may cause dizziness or lightheadedness
• Avoid abrupt withdrawal
• Monitor liver function regularly
• Never take the medicine with a glass of grapefruit juice since the blood pressure may be decreased excessively